20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway. [electronic resource]
Producer: 20160603Description: 3969-87 p. digitalISSN:- 1177-8881
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cellular Senescence -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Dose-Response Relationship, Drug
- Gallbladder Neoplasms -- drug therapy
- Ginsenosides -- pharmacology
- Humans
- Mice, Inbred BALB C
- Mice, Nude
- Mitochondria -- drug effects
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Tumor Burden -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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