Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation. [electronic resource]
Producer: 20160614Description: e0136527 p. digitalISSN:- 1932-6203
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Astrocytoma -- drug therapy
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- biosynthesis
- DNA Damage -- drug effects
- DNA-Binding Proteins -- metabolism
- Histones -- metabolism
- Humans
- Lactones -- pharmacology
- Nuclear Proteins -- metabolism
- Phosphorylation -- drug effects
- Secondary Metabolism
- Sesquiterpenes -- pharmacology
- Tumor Protein p73
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor Proteins -- metabolism
- bcl-2-Associated X Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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