Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma. [electronic resource]
Producer: 20160301Description: 3153-3162 p. digitalISSN:- 1523-1747
- Adult
- Collagen
- Dinoprost -- analogs & derivatives
- Drug Combinations
- Endothelial Cells -- physiology
- Female
- Focal Adhesion Protein-Tyrosine Kinases -- metabolism
- Humans
- Laminin
- Male
- Middle Aged
- Neovascularization, Physiologic
- Oxidative Stress
- Phosphorylation
- Proteoglycans
- Receptors, Thromboxane A2, Prostaglandin H2 -- drug effects
- Scleroderma, Systemic -- physiopathology
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
- rho-Associated Kinases -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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