Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice. [electronic resource]
Producer: 20160815Description: 554-62 p. digitalISSN:- 2352-3964
- Animals
- Apoptosis -- drug effects
- Bone Marrow Transplantation
- Cell Line, Tumor
- Combined Modality Therapy -- methods
- Disease-Free Survival
- Fusion Proteins, bcr-abl -- genetics
- Gene Expression -- drug effects
- Humans
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Liposomes -- therapeutic use
- Mice
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Mice, SCID
- Mice, Transgenic
- Nanoparticles
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- mortality
- Protein Kinase Inhibitors -- therapeutic use
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Radiation Tolerance -- drug effects
- Radiation-Sensitizing Agents -- therapeutic use
- Syk Kinase
- Treatment Outcome
- Whole-Body Irradiation
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.