Selection of High-Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protease Fusions. [electronic resource]
Producer: 20151221Description: 3110-22 p. digitalISSN:- 1089-8638
- Amino Acid Sequence
- Animals
- Cell Line
- Crystallography, X-Ray
- Drug Discovery
- Entropy
- Humans
- Mice
- Molecular Sequence Data
- Peptide Library
- Peptides, Cyclic -- chemistry
- Protein Conformation
- Recombinant Fusion Proteins -- chemistry
- Serine Endopeptidases -- chemistry
- Serine Proteinase Inhibitors -- chemistry
- Urokinase-Type Plasminogen Activator -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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