Dickkopf-3 (DKK-3) obstructs VEGFR-2/Akt/mTOR signaling cascade by interacting of β2-microglobulin (β2M) in ovarian tumorigenesis. [electronic resource]
Producer: 20160630Description: 2150-9 p. digitalISSN:- 1873-3913
- Adaptor Proteins, Signal Transducing
- Apoptosis -- genetics
- Cell Cycle Checkpoints -- genetics
- Cell Line, Tumor
- Cell Proliferation -- genetics
- Cell Transformation, Neoplastic -- pathology
- Chemokines
- Female
- HEK293 Cells
- Human Umbilical Vein Endothelial Cells
- Humans
- Intercellular Signaling Peptides and Proteins -- metabolism
- Luciferases -- metabolism
- Neoplasm Metastasis -- pathology
- Neovascularization, Pathologic -- pathology
- Ovarian Neoplasms -- pathology
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA Interference
- RNA, Small Interfering
- Signal Transduction -- genetics
- TOR Serine-Threonine Kinases -- metabolism
- Vascular Endothelial Growth Factor Receptor-1 -- metabolism
- Vascular Endothelial Growth Factor Receptor-2 -- metabolism
- beta 2-Microglobulin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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