Loss of long-chain acyl-CoA synthetase isoform 1 impairs cardiac autophagy and mitochondrial structure through mechanistic target of rapamycin complex 1 activation. [electronic resource]
Producer: 20160211Description: 4641-53 p. digitalISSN:- 1530-6860
- Animals
- Autophagy -- drug effects
- Coenzyme A Ligases -- deficiency
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Mice, Knockout
- Mitochondria, Heart -- genetics
- Multiprotein Complexes -- genetics
- Myocardium -- metabolism
- Oxygen Consumption -- drug effects
- Proton-Translocating ATPases -- metabolism
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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