Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation. [electronic resource]
Producer: 20160725Description: 25646-59 p. digitalISSN:- 1949-2553
- Antineoplastic Agents -- metabolism
- Apoptosis -- drug effects
- Arsenic Trioxide
- Arsenicals -- metabolism
- Biotransformation
- Cacodylic Acid -- analogs & derivatives
- Cell Differentiation -- drug effects
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- HEK293 Cells
- HeLa Cells
- Humans
- Leukemia, Promyelocytic, Acute -- drug therapy
- Methylation
- Nuclear Proteins -- metabolism
- Oncogene Proteins, Fusion -- metabolism
- Organometallic Compounds -- metabolism
- Oxides -- metabolism
- Promyelocytic Leukemia Protein
- Proteasome Endopeptidase Complex -- metabolism
- Protein Binding
- Protein Interaction Domains and Motifs
- Proteolysis
- Sumoylation
- Time Factors
- Transcription Factors -- metabolism
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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