The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients. [electronic resource]
Producer: 20151117Description: 809-22 p. digitalISSN:- 1470-8736
- Animals
- Antineoplastic Agents -- pharmacology
- Breast Neoplasms -- drug therapy
- CD24 Antigen -- metabolism
- Drug Resistance, Neoplasm -- drug effects
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Hedgehog Proteins -- metabolism
- Humans
- Hyaluronan Receptors -- metabolism
- Kaplan-Meier Estimate
- Kruppel-Like Transcription Factors -- genetics
- MCF-7 Cells
- Mice, Inbred BALB C
- Mice, Nude
- Neoplastic Stem Cells -- drug effects
- Nuclear Proteins -- genetics
- Paclitaxel -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Proto-Oncogene Proteins c-myc -- genetics
- Pyrans -- pharmacology
- Receptors, G-Protein-Coupled -- genetics
- Signal Transduction
- Smoothened Receptor
- Spheroids, Cellular -- drug effects
- Transcription Factors -- genetics
- Xenograft Model Antitumor Assays
- Zinc Finger Protein GLI1
- Zinc Finger Protein Gli2
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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