Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis. [electronic resource]
Producer: 20151117Description: 9716-21 p. digitalISSN:- 1091-6490
- Animals
- Apoptosis -- drug effects
- Biphenyl Compounds -- pharmacology
- Caspase 3 -- metabolism
- Cell Line
- Cell Movement -- drug effects
- Cell Survival -- drug effects
- Disease Models, Animal
- Endometriosis -- drug therapy
- Endometrium -- blood supply
- Estrogens -- biosynthesis
- Female
- Humans
- Inflammation -- pathology
- Mice
- Neovascularization, Pathologic -- metabolism
- Pelvic Pain -- drug therapy
- Poly(ADP-ribose) Polymerases -- metabolism
- Progesterone -- metabolism
- Receptors, Prostaglandin E, EP2 Subtype -- antagonists & inhibitors
- Receptors, Prostaglandin E, EP4 Subtype -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Steroids -- therapeutic use
- Xanthones -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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