PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2. [electronic resource]
Producer: 20151022Description: 1024-35 p. digitalISSN:- 1476-4679
- Amino Acid Motifs
- Animals
- Binding Sites
- CDC2 Protein Kinase
- COS Cells
- Cell Cycle Proteins -- genetics
- Centrosome -- enzymology
- Chlorocebus aethiops
- Cyclin-Dependent Kinases -- metabolism
- Enzyme Activation
- HEK293 Cells
- HeLa Cells
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Microtubules -- enzymology
- Mitosis
- Mutation
- Nerve Tissue Proteins -- genetics
- Phosphorylation
- Protein Binding
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- RNA Interference
- Serine
- Signal Transduction
- Spindle Apparatus -- enzymology
- Time Factors
- Transfection
- Tubulin -- metabolism
- Polo-Like Kinase 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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