D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. [electronic resource]
Producer: 20160413Description: 7768 p. digitalISSN:- 2041-1723
- Alcohol Oxidoreductases -- genetics
- Blotting, Western
- Cell Line, Tumor
- DNA Methylation -- genetics
- Dioxygenases -- metabolism
- Epigenesis, Genetic
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- Histones -- metabolism
- Humans
- Hydroxylation -- genetics
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Isocitrate Dehydrogenase -- genetics
- Ketoglutaric Acids -- metabolism
- Lymphoma, Large B-Cell, Diffuse -- genetics
- Methylation
- Real-Time Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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