Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. [electronic resource]
Producer: 20151006Description: 471-82 p. digitalISSN:- 1521-0103
- Animals
- Binding Sites -- drug effects
- Brain -- drug effects
- CHO Cells
- Cell Line
- Cricetulus
- Dopamine -- metabolism
- HEK293 Cells
- Humans
- Hypnotics and Sedatives -- pharmacology
- Male
- Mice
- Mice, Knockout
- Orexin Receptor Antagonists
- Pyridines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Sleep -- drug effects
- Sleep Initiation and Maintenance Disorders -- drug therapy
- Sleep Stages -- drug effects
- Sleep, REM -- drug effects
- Zolpidem
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Publication Type: Journal Article
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