Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model. [electronic resource]
Producer: 20160209Description: 187-94 p. digitalISSN:- 1097-0215
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Central Nervous System Neoplasms -- immunology
- Disease Models, Animal
- Female
- Glioblastoma -- immunology
- Humans
- Immunologic Memory
- Immunotherapy
- Interleukin-15 -- agonists
- Lymphocytes, Tumor-Infiltrating -- immunology
- Mice
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
- Proteins -- pharmacology
- Radiosurgery
- Recombinant Fusion Proteins
- T-Lymphocyte Subsets -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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