mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress. [electronic resource]
Producer: 20160706Description: 1377-88 p. digitalISSN:- 1557-3125
- Animals
- Cell Line, Tumor
- Endoplasmic Reticulum Stress -- drug effects
- Eukaryotic Initiation Factor-2 -- metabolism
- Fibrosarcoma -- drug therapy
- Humans
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Multiprotein Complexes -- antagonists & inhibitors
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Serine -- metabolism
- Signal Transduction
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Transfection
- Up-Regulation
- eIF-2 Kinase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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