Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions. [electronic resource]
Producer: 20151126Description: 2504-16 p. digitalISSN:- 1521-4141
- CD4-Positive T-Lymphocytes -- cytology
- CD8-Positive T-Lymphocytes -- cytology
- Cell Proliferation -- drug effects
- Deoxyglucose -- pharmacology
- Glucose -- deficiency
- Glycolysis -- drug effects
- Humans
- Interferon-gamma -- biosynthesis
- Interleukin-10 -- biosynthesis
- Interleukin-2 -- biosynthesis
- Interleukin-4 -- biosynthesis
- Mitochondria -- drug effects
- Monocytes -- cytology
- Oxidative Phosphorylation -- drug effects
- Primary Cell Culture
- T-Lymphocyte Subsets -- cytology
- Tumor Necrosis Factor-alpha -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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