Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development. [electronic resource]
Producer: 20160706Description: 1361-6 p. digitalISSN:- 1557-3125
- Aminohydrolases -- biosynthesis
- Animals
- Antineoplastic Agents -- chemistry
- Cell Proliferation -- drug effects
- Drug Design
- Humans
- Methylenetetrahydrofolate Dehydrogenase (NADP) -- biosynthesis
- Mice
- Mitochondria -- enzymology
- Models, Molecular
- Molecular Targeted Therapy
- Multienzyme Complexes -- biosynthesis
- Neoplasms -- drug therapy
- Protein Conformation
- Protein Folding
- Structure-Activity Relationship
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Publication Type: Journal Article
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