The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts. [electronic resource]
Producer: 20160222Description: 474 p. digitalISSN:- 1471-2407
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dimethyl Sulfoxide -- administration & dosage
- Estrogen Receptor alpha -- genetics
- Female
- Humans
- Janus Kinase 2 -- antagonists & inhibitors
- Neoplasm Metastasis
- Receptors, Somatomedin -- antagonists & inhibitors
- STAT5 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Sulfones -- administration & dosage
- Tamoxifen -- administration & dosage
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.