CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism. [electronic resource]
Producer: 20170630Description: 1175-85 p. digitalISSN:- 1468-3288
- Actins -- analysis
- Angiogenesis Inducing Agents -- pharmacology
- Animals
- Antigens, CD -- analysis
- Antigens, Neoplasm -- analysis
- Becaplermin
- Carbon Tetrachloride
- Cell Proliferation -- drug effects
- Cells, Cultured
- Chemical and Drug Induced Liver Injury -- metabolism
- Chronic Disease
- Collagen -- metabolism
- Desmin -- analysis
- Fibrosis
- Gene Expression
- Hepatic Stellate Cells -- chemistry
- Humans
- Inflammation -- genetics
- Liver -- chemistry
- Liver Cirrhosis -- chemically induced
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neovascularization, Pathologic -- genetics
- Platelet-Derived Growth Factor -- metabolism
- Proto-Oncogene Proteins c-fos -- metabolism
- Proto-Oncogene Proteins c-sis -- pharmacology
- RNA, Messenger -- metabolism
- Receptor, Platelet-Derived Growth Factor alpha -- metabolism
- Receptor, Platelet-Derived Growth Factor beta -- metabolism
- Signal Transduction -- genetics
- Transforming Growth Factor beta -- genetics
- Vimentin -- analysis
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Publication Type: Journal Article
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