Famitinib enhances nasopharyngeal cancer cell radiosensitivity by attenuating radiation-induced phosphorylation of platelet-derived growth factor receptor and c-kit and inhibiting microvessel formation. [electronic resource]
Producer: 20160408Description: 771-6 p. digitalISSN:- 1362-3095
- Animals
- Carcinoma
- Cell Line, Tumor
- Female
- Humans
- Indoles -- pharmacology
- Mice
- Mice, Nude
- Microvessels -- drug effects
- Nasopharyngeal Carcinoma
- Nasopharyngeal Neoplasms -- drug therapy
- Neovascularization, Pathologic -- prevention & control
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-kit -- metabolism
- Pyrroles -- pharmacology
- Radiation Tolerance -- drug effects
- Receptor, Platelet-Derived Growth Factor beta -- metabolism
- Tumor Stem Cell Assay
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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