Synthesis and evaluation of 8,4'-dideshydroxy-leinamycin revealing new insights into the structure-activity relationship of the anticancer natural product leinamycin. [electronic resource]
Producer: 20160620Description: 4899-4902 p. digitalISSN:- 1464-3405
- Antibiotics, Antineoplastic -- chemical synthesis
- Biological Products -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Lactams -- chemical synthesis
- Molecular Conformation
- Streptomyces -- chemistry
- Structure-Activity Relationship
- Thiazoles -- chemical synthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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