Synthesis of targeted dibenzo[b,f]thiepines and dibenzo[b,f]oxepines as potential lead molecules with promising anti-breast cancer activity. [electronic resource]
Producer: 20160314Description: 113-24 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Benzoxepins -- chemical synthesis
- Breast Neoplasms -- drug therapy
- Catalytic Domain
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Chemistry Techniques, Synthetic
- Dibenzothiepins -- chemical synthesis
- Drug Design
- Estrogen Receptor alpha -- chemistry
- Humans
- L-Lactate Dehydrogenase -- metabolism
- MCF-7 Cells
- Molecular Docking Simulation
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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