Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitus. [electronic resource]
Producer: 20150819Description: 8829-42 p. digitalISSN:- 1529-2401
- Animals
- Animals, Newborn
- Anticonvulsants -- chemistry
- Carbamates -- chemistry
- Disease Models, Animal
- Epilepsy -- drug therapy
- Evoked Potentials, Auditory, Brain Stem -- genetics
- Female
- HEK293 Cells
- Homeodomain Proteins -- genetics
- Humans
- In Vitro Techniques
- KCNQ Potassium Channels -- genetics
- KCNQ2 Potassium Channel -- agonists
- Male
- Membrane Potentials -- drug effects
- Mice
- Mice, Inbred ICR
- Mice, Knockout
- Mutation -- genetics
- Phenylenediamines -- chemistry
- Rats
- Rats, Sprague-Dawley
- Tinnitus -- etiology
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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