Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner. [electronic resource]
Producer: 20160621Description: 101-15 p. digitalISSN:- 1096-1186
- AMP-Activated Protein Kinases -- deficiency
- Animals
- Aorta, Thoracic -- drug effects
- Apoptosis -- drug effects
- Cardiovascular Diseases -- drug therapy
- Carrier Proteins -- metabolism
- Caspase 3 -- metabolism
- Cell Line
- Drugs, Chinese Herbal -- pharmacology
- Endoplasmic Reticulum Stress -- drug effects
- Endothelial Cells -- cytology
- Gene Knockdown Techniques
- Humans
- Ilex
- Inflammasomes -- drug effects
- Lipid Metabolism -- drug effects
- Male
- Mice
- Mice, Inbred ICR
- Mitochondria -- drug effects
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Thioredoxins -- metabolism
- Triterpenes -- pharmacology
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.