Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. [electronic resource]
Producer: 20150914Description: 86-92 p. digitalISSN:- 1096-0333
- Alanine Transaminase -- blood
- Animals
- Antineoplastic Agents -- administration & dosage
- Aptamers, Nucleotide -- administration & dosage
- Aspartate Aminotransferases -- blood
- Biomarkers -- blood
- Chemical and Drug Induced Liver Injury -- blood
- Complement C3a -- metabolism
- Complement C5a -- metabolism
- Cytokines -- blood
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- E-Selectin -- drug effects
- Female
- Injections, Intravenous
- Kidney -- drug effects
- Liver -- drug effects
- Male
- Mice, Inbred ICR
- Necrosis
- Risk Assessment
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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