Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds. [electronic resource]
Producer: 20170124Description: 1225-37 p. digitalISSN:- 1432-0738
- Animals
- Biological Assay -- methods
- Biological Transport
- Cell Differentiation -- drug effects
- Cell Line
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Embryonic Stem Cells -- drug effects
- Female
- Fetus -- drug effects
- Gestational Age
- Humans
- Kinetics
- Maternal Exposure
- Mice
- Models, Biological
- Pregnancy
- Rats
- Rats, Wistar
- Reproducibility of Results
- Risk Assessment
- Triazoles -- metabolism
- Trophoblasts -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
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