Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells. [electronic resource]
Producer: 20160429Description: 15464-81 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Astrocytes -- metabolism
- Brain Neoplasms -- drug therapy
- Cell Line, Tumor
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Glioma -- drug therapy
- Histocompatibility Antigens Class I -- biosynthesis
- Humans
- Killer Cells, Natural -- immunology
- Mice
- Mice, Nude
- Piperidines -- pharmacology
- Pyrazoles -- pharmacology
- RNA Interference
- RNA, Small Interfering
- Receptor, Cannabinoid, CB1 -- antagonists & inhibitors
- Rimonabant
- STAT3 Transcription Factor -- antagonists & inhibitors
- Transforming Growth Factor beta1 -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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