The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson's disease. [electronic resource]
Producer: 20160510Description: 86-94 p. digitalISSN:- 1873-7064
- 3,4-Dihydroxyphenylacetic Acid -- metabolism
- 5-alpha Reductase Inhibitors -- pharmacology
- Animals
- Corpus Striatum -- drug effects
- Dihydrotestosterone -- blood
- Dopamine -- metabolism
- Dopamine Plasma Membrane Transport Proteins -- metabolism
- Dopaminergic Neurons -- drug effects
- Dose-Response Relationship, Drug
- Dutasteride -- pharmacology
- Finasteride -- pharmacology
- Homovanillic Acid -- metabolism
- MPTP Poisoning -- drug therapy
- Male
- Mice, Inbred C57BL
- Neuroprotective Agents -- pharmacology
- Pars Compacta -- drug effects
- RNA, Messenger -- metabolism
- Testosterone -- blood
- Time Factors
- Tyrosine 3-Monooxygenase -- metabolism
- Vesicular Monoamine Transport Proteins -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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