K356dup--an in-frame insertion in the BCR-ABL gene in an imatinib-resistant chronic myeloid leukemia. [electronic resource]
Producer: 20151120Description: e3-6 p. digitalISSN:- 1751-553X
- Dasatinib -- therapeutic use
- Drug Resistance, Neoplasm -- genetics
- Female
- Fusion Proteins, bcr-abl -- antagonists & inhibitors
- Gene Expression Regulation, Leukemic -- drug effects
- Humans
- Imatinib Mesylate -- chemistry
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- drug therapy
- Models, Molecular
- Mutagenesis, Insertional
- Protein Binding
- Protein Kinase Inhibitors -- chemistry
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-abl -- antagonists & inhibitors
- Reverse Transcriptase Polymerase Chain Reaction
- Young Adult
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Publication Type: Case Reports; Letter
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