Pelitinib (EKB-569) targets the up-regulation of ABCB1 and ABCG2 induced by hyperthermia to eradicate lung cancer. [electronic resource]
Producer: 20160512Description: 4089-106 p. digitalISSN:- 1476-5381
- ATP Binding Cassette Transporter, Subfamily B -- genetics
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Adenosine Triphosphatases -- metabolism
- Aminoquinolines -- pharmacology
- Aniline Compounds -- pharmacology
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- antagonists & inhibitors
- Humans
- Hyperthermia, Induced
- Lung Neoplasms -- drug therapy
- Multidrug Resistance-Associated Proteins -- genetics
- Neoplasm Proteins -- genetics
- Protein Kinase Inhibitors -- pharmacology
- Topotecan -- pharmacology
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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