Early lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model. [electronic resource]
Producer: 20160427Description: e1005211 p. digitalISSN:- 1553-7404
- ADP-ribosyl Cyclase 1 -- metabolism
- Alleles
- Animals
- Antigens, CD34 -- metabolism
- Cell Lineage
- Cell Proliferation
- Chromosomes, Human, Pair 21 -- genetics
- Disease Models, Animal
- Down Syndrome -- genetics
- Erythroid Cells -- metabolism
- Gene Expression Profiling
- Gene Expression Regulation
- Genotype
- Hematopoiesis -- genetics
- Hematopoietic System -- cytology
- Humans
- Megakaryocytes -- metabolism
- Mice
- Mice, Knockout
- Microarray Analysis
- Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-ets -- genetics
- Sequence Analysis, RNA
- Stem Cells -- cytology
- Trans-Activators -- genetics
- Transcription Factors -- genetics
- Transcriptional Regulator ERG
- Transcriptome
- Trisomy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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