XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death. [electronic resource]
Producer: 20160218Description: e1763 p. digitalISSN:- 2041-4889
- Animals
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Cell Line
- DNA-Binding Proteins -- genetics
- Endoplasmic Reticulum -- pathology
- Endoplasmic Reticulum Stress -- drug effects
- Female
- Gentamicins -- pharmacology
- HEK293 Cells
- Hair Cells, Auditory -- pathology
- Hearing Loss, High-Frequency -- chemically induced
- Humans
- Male
- Membrane Glycoproteins -- metabolism
- Mice
- Mice, Inbred CBA
- Neurons -- pathology
- Protein Biosynthesis -- drug effects
- Protein Folding
- Proteostasis Deficiencies
- RNA Splicing -- genetics
- Regulatory Factor X Transcription Factors
- Spiral Ganglion -- cytology
- Taurochenodeoxycholic Acid -- pharmacology
- Transcription Factors -- genetics
- Unfolded Protein Response -- genetics
- X-Box Binding Protein 1
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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