Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma. [electronic resource]
Producer: 20160915Description: 197-210 p. digitalISSN:- 1537-4513
- Animals
- Cell Line
- Cell- and Tissue-Based Therapy
- Chemokine CXCL12 -- biosynthesis
- Chemotaxis -- genetics
- Cytotoxicity, Immunologic
- Disease Models, Animal
- Ectopic Gene Expression
- ErbB Receptors -- immunology
- Female
- Gene Expression
- Gene Order
- Genetic Therapy
- Genetic Vectors -- administration & dosage
- Glioblastoma -- etiology
- Humans
- Immunotherapy
- Killer Cells, Natural -- immunology
- Lentivirus -- genetics
- Mice
- Receptors, Antigen, T-Cell -- genetics
- Receptors, CXCR4 -- genetics
- Recombinant Fusion Proteins -- genetics
- Transduction, Genetic
- Tumor Burden
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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