Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6. [electronic resource]
Producer: 20160321Description: 122-32 p. digitalISSN:- 1791-2423
- Cell Line, Tumor
- Cell Survival -- drug effects
- Down-Regulation
- Drug Synergism
- ErbB Receptors -- antagonists & inhibitors
- Female
- Gefitinib
- Humans
- Indoles -- pharmacology
- Peptide Library
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- Quinazolines -- pharmacology
- Ribosomal Protein S6 -- metabolism
- Sulfonamides -- pharmacology
- Triple Negative Breast Neoplasms -- drug therapy
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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