ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics. [electronic resource]
Producer: 20150825Description: 68-81 p. digitalISSN:- 1090-2422
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Apoptosis -- drug effects
- Bile Duct Neoplasms -- drug therapy
- Bile Ducts, Intrahepatic
- Biphenyl Compounds -- administration & dosage
- Cell Line
- Cell Survival -- drug effects
- Cholangiocarcinoma -- drug therapy
- Cisplatin -- administration & dosage
- Drug Resistance, Neoplasm -- drug effects
- Dynamins
- GTP Phosphohydrolases -- metabolism
- Humans
- Membrane Proteins -- metabolism
- Membrane Transport Proteins -- metabolism
- Microtubule-Associated Proteins -- metabolism
- Mitochondria -- metabolism
- Mitochondrial Dynamics -- drug effects
- Mitochondrial Precursor Protein Import Complex Proteins
- Mitochondrial Proteins -- metabolism
- Mitophagy -- drug effects
- Myeloid Cell Leukemia Sequence 1 Protein -- biosynthesis
- Nitrophenols -- administration & dosage
- Piperazines -- administration & dosage
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- genetics
- RNA-Binding Proteins -- genetics
- Receptors, Cell Surface -- metabolism
- Sulfonamides -- administration & dosage
- bcl-2 Homologous Antagonist-Killer Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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