Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization. [electronic resource]
Producer: 20150929Description: 17041-54 p. digitalISSN:- 1083-351X
- ADAM Proteins -- chemistry
- ADAM10 Protein
- ADAM17 Protein
- Amyloid Precursor Protein Secretases -- chemistry
- Animals
- Cattle
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Cells, Cultured
- HEK293 Cells
- Humans
- Hyaluronan Receptors -- chemistry
- Membrane Proteins -- chemistry
- Mice
- Mice, Knockout
- Models, Biological
- Mutagenesis, Site-Directed
- NIH 3T3 Cells
- Neuregulin-1 -- chemistry
- Protein Multimerization
- Protein Structure, Tertiary
- Proteolysis
- Rats
- Recombinant Fusion Proteins -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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