Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells. [electronic resource]
Producer: 20160229Description: 10728-45 p. digitalISSN:- 1949-2553
- Antineoplastic Agents -- pharmacology
- Antioxidants -- metabolism
- Autophagy -- drug effects
- Breast Neoplasms -- drug therapy
- Cellular Senescence -- drug effects
- Coculture Techniques
- Cytokines -- metabolism
- Dose-Response Relationship, Drug
- Female
- Fibroblasts -- drug effects
- Glycolysis -- drug effects
- Hedgehog Proteins -- metabolism
- Humans
- Inflammation Mediators -- metabolism
- MCF-7 Cells
- Neoplastic Stem Cells -- drug effects
- Oxidative Stress -- drug effects
- Paracrine Communication -- drug effects
- Phenotype
- Signal Transduction -- drug effects
- Time Factors
- Transcription Factors -- metabolism
- Transfection
- Tumor Microenvironment
- Zinc Finger Protein GLI1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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