Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice. [electronic resource]
Producer: 20150831Description: 565-77.e1-10 p. digitalISSN:- 1873-2399
- Animals
- B-Lymphocytes -- pathology
- Bone Marrow Cells -- metabolism
- Cell Division
- Cell Nucleus -- metabolism
- Cell Transformation, Neoplastic -- genetics
- Cells, Cultured
- Colony-Forming Units Assay
- GATA2 Transcription Factor -- genetics
- Gene Expression Regulation, Leukemic -- drug effects
- Genes, Synthetic
- Genes, myc
- Hematopoietic Stem Cells -- cytology
- Homeodomain Proteins -- genetics
- Humans
- Leukemia, Myeloid, Acute -- genetics
- Lymphopoiesis -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- Myeloid Cells -- metabolism
- Myelopoiesis -- genetics
- Receptors, Estrogen -- genetics
- Recombinant Fusion Proteins -- metabolism
- T-Lymphocytes -- pathology
- Tamoxifen -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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