Inhibition of the mammalian target of rapamycin complex 1 signaling pathway reduces itch behaviour in mice. [electronic resource]
Producer: 20160502Description: 1519-1529 p. digitalISSN:- 1872-6623
- Animals
- Disease Models, Animal
- Gastrin-Releasing Peptide -- metabolism
- Histamine -- metabolism
- Hypoglycemic Agents -- pharmacology
- Male
- Mechanistic Target of Rapamycin Complex 1
- Metformin -- pharmacology
- Mice
- Mice, Inbred C57BL
- Multiprotein Complexes -- metabolism
- Neuralgia -- chemically induced
- Phosphoproteins -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Pruritus -- chemically induced
- Signal Transduction -- drug effects
- Sirolimus -- analogs & derivatives
- Skin -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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