Rosiglitazone attenuates the metalloprotease/anti-metalloprotease imbalance in emphysema induced by cigarette smoke: involvement of extracellular signal-regulated kinase and NFκB signaling. [electronic resource]
Producer: 20160204Description: 715-24 p. digitalISSN:- 1178-2005
- Administration, Oral
- Animals
- Apoptosis -- drug effects
- Cytoprotection
- Disease Models, Animal
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- I-kappa B Proteins -- metabolism
- Inhalation Exposure
- Lung -- drug effects
- Male
- Matrix Metalloproteinase 2 -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- PPAR gamma -- agonists
- Phosphorylation
- Pulmonary Emphysema -- enzymology
- Rats, Wistar
- Rosiglitazone
- Signal Transduction -- drug effects
- Smoke -- adverse effects
- Thiazolidinediones -- administration & dosage
- Tobacco Smoke Pollution -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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