A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice. [electronic resource]
Producer: 20160217Description: 229-33 p. digitalISSN:- 1537-6524
- Acetylcholinesterase -- blood
- Animals
- Animals, Outbred Strains
- Antidotes -- therapeutic use
- Atropine -- therapeutic use
- Brain -- drug effects
- Cholinesterase Inhibitors -- administration & dosage
- Cholinesterase Reactivators -- therapeutic use
- Diaphragm -- drug effects
- Dose-Response Relationship, Drug
- Drug Therapy, Combination
- Male
- Mice
- Muscarinic Antagonists -- therapeutic use
- Nerve Tissue Proteins -- agonists
- Neurons -- drug effects
- Neurotoxicity Syndromes -- blood
- Obidoxime Chloride -- therapeutic use
- Oximes -- therapeutic use
- Pyridinium Compounds -- therapeutic use
- Rats, Wistar
- Sarin -- administration & dosage
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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