Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells. [electronic resource]
Producer: 20160412Description: 1395-403 p. digitalISSN:- 1538-8514
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Blotting, Western
- Cell Line
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Flavonoids -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Homeodomain Proteins -- genetics
- Humans
- Inhibitor of Apoptosis Proteins -- genetics
- Pancreatic Neoplasms -- genetics
- Propiophenones -- pharmacology
- Receptor, Notch1 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Survivin
- Time Factors
- Transcription Factor HES-1
- Tumor Stem Cell Assay
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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