Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex. [electronic resource]
Producer: 20160405Description: 6842 p. digitalISSN:- 2041-1723
- Animals
- Brain -- cytology
- COS Cells
- Chlorocebus aethiops
- Dendritic Spines -- metabolism
- Ephrin-B3 -- metabolism
- Guanosine Diphosphate -- metabolism
- HEK293 Cells
- Hippocampus -- cytology
- Humans
- Immunoprecipitation
- Mice
- Mice, Knockout
- Microscopy, Confocal
- Monomeric GTP-Binding Proteins -- metabolism
- Neurons -- cytology
- Neuropeptides -- metabolism
- Patch-Clamp Techniques
- Ras Homolog Enriched in Brain Protein
- Rats
- Synapses -- metabolism
- Syntenins -- metabolism
- Tuberous Sclerosis -- metabolism
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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