Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases. [electronic resource]
Producer: 20161213Description: 972-83 p. digitalISSN:- 1943-3670
- Alveolar Bone Loss -- microbiology
- Animals
- Anti-Inflammatory Agents -- therapeutic use
- Bacteroidaceae Infections -- immunology
- Biphenyl Compounds -- therapeutic use
- Cathepsin K -- antagonists & inhibitors
- Disease Models, Animal
- Epithelial Cells -- drug effects
- Female
- Gingiva -- drug effects
- Gram-Negative Bacterial Infections -- immunology
- Immunity, Innate -- drug effects
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred Strains
- Osteoclasts -- drug effects
- Periodontitis -- microbiology
- Porphyromonas gingivalis -- immunology
- T-Lymphocytes -- drug effects
- Tannerella forsythia -- immunology
- Toll-Like Receptor 4 -- antagonists & inhibitors
- Toll-Like Receptor 5 -- antagonists & inhibitors
- Toll-Like Receptor 9 -- antagonists & inhibitors
- Treponema denticola -- immunology
- Treponemal Infections -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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