A novel transcriptional factor Nkapl is a germ cell-specific suppressor of Notch signaling and is indispensable for spermatogenesis. [electronic resource]
Producer: 20160419Description: e0124293 p. digitalISSN:- 1932-6203
- Animals
- Apoptosis
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Cell Differentiation
- Cell Line
- Cell Nucleus -- metabolism
- Co-Repressor Proteins -- genetics
- Germ Cells -- cytology
- HEK293 Cells
- Homeodomain Proteins -- genetics
- Humans
- Male
- Mice
- Mice, Inbred ICR
- Nuclear Proteins -- deficiency
- Phenotype
- Protein Binding
- RNA, Messenger -- metabolism
- Real-Time Polymerase Chain Reaction
- Receptors, Notch -- metabolism
- Repressor Proteins -- genetics
- Signal Transduction
- Spermatogenesis
- Spermatozoa -- metabolism
- Testis -- metabolism
- Transcription Factor HES-1
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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