Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain. [electronic resource]
Producer: 20150818Description: 656-79 p. digitalISSN:- 0006-3002
- Computer Simulation
- Cytochrome b Group -- metabolism
- Cytochromes c -- metabolism
- Electron Transport
- Electron Transport Complex III -- antagonists & inhibitors
- Humans
- Hydrogen-Ion Concentration
- Iron-Sulfur Proteins -- antagonists & inhibitors
- Kinetics
- Membrane Potential, Mitochondrial
- Mitochondria -- metabolism
- Models, Theoretical
- Multienzyme Complexes -- antagonists & inhibitors
- NADH, NADPH Oxidoreductases -- antagonists & inhibitors
- Oxidation-Reduction
- Oxygen Consumption
- Quinones -- metabolism
- Superoxides -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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