Synthesis and biological evaluation of open-chain analogs of cyclic peptides as inhibitors of cellular Shp2 activity. [electronic resource]
Producer: 20160126Description: 2562-7 p. digitalISSN:- 1464-3391
- Acetylcholinesterase -- chemistry
- Catalytic Domain
- Cathepsin B -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Enzyme Assays
- Enzyme Inhibitors -- chemical synthesis
- GPI-Linked Proteins -- antagonists & inhibitors
- Gene Expression
- HeLa Cells
- Humans
- IMP Dehydrogenase -- antagonists & inhibitors
- Kinetics
- Molecular Docking Simulation
- Peptides, Cyclic -- chemical synthesis
- Proteasome Endopeptidase Complex -- drug effects
- Protein Binding
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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