N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. [electronic resource]
Producer: 20160331Description: e0122650 p. digitalISSN:- 1932-6203
- Alleles
- Amino Acid Sequence
- Animals
- COS Cells
- Calcinosis -- metabolism
- Chlorocebus aethiops
- Codon, Nonsense
- Disease Models, Animal
- Endoplasmic Reticulum -- metabolism
- Ethylnitrosourea -- toxicity
- Fibroblast Growth Factor-23
- Fibroblast Growth Factors -- blood
- Genetic Loci
- Genotype
- Glucuronidase -- chemistry
- Humans
- Kidney -- metabolism
- Klotho Proteins
- Longevity -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Mutation, Missense
- N-Acetylgalactosaminyltransferases -- genetics
- Phenotype
- Phosphates -- blood
- Polymorphism, Single Nucleotide
- Sequence Alignment
- Vitamin D -- analogs & derivatives
- Polypeptide N-acetylgalactosaminyltransferase
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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