Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin. [electronic resource]
Producer: 20150629Description: 107-15 p. digitalISSN:- 1879-3169
- Animals
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Constitutive Androstane Receptor
- Cytochrome P-450 CYP3A -- biosynthesis
- Cytochrome P-450 CYP3A Inducers -- pharmacology
- Cytochrome P-450 Enzyme Inducers -- pharmacology
- Cytochrome P-450 Enzyme System -- biosynthesis
- Cytochrome P450 Family 2
- Enzyme Induction
- Glucuronosyltransferase -- metabolism
- Humans
- Isoenzymes
- Liver -- drug effects
- Male
- Membrane Proteins -- biosynthesis
- Mice, Inbred C57BL
- Mice, Transgenic
- Microsomes, Liver -- drug effects
- Pregnane X Receptor
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, Steroid -- agonists
- Rifampin -- pharmacology
- Steroid Hydroxylases -- biosynthesis
- Substrate Specificity
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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