TBX21-1993T/C (rs4794067) polymorphism is associated with increased risk of chronic periodontitis and increased T-bet expression in periodontal lesions, but does not significantly impact the IFN-g transcriptional level or the pattern of periodontophatic bacterial infection. [electronic resource]
Producer: 20160122Description: 293-304 p. digitalISSN:- 2150-5608
- Bacterial Infections -- microbiology
- Bacterial Load
- Case-Control Studies
- Chronic Periodontitis -- genetics
- Female
- Genetic Predisposition to Disease
- Genotype
- Gingivitis -- genetics
- Heterozygote
- Homozygote
- Humans
- Interferon-gamma -- genetics
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- T-Box Domain Proteins -- genetics
- Up-Regulation
- T-bet Transcription Factor
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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